Inflammaging (Inflammation + Aging): The Silent Skin Saboteur

As an aesthetic doctor focused on regenerative medicine, I often tell my patients that the greatest threat to youthful skin isn’t just the sun or time—it’s inflammation. Specifically, inflammaging, a term that describes chronic, low-grade inflammation that accelerates skin aging from within.

What Is Inflammaging (Inflammation + Aging)?

Inflammaging is the cumulative result of oxidative stress, environmental toxins, poor diet, stress, sedentary lifestyle, and hormonal shifts. These factors trigger a persistent inflammatory response in the body, which leads to the breakdown of collagen, elastin, and hyaluronic acid—essential components for firm, glowing skin. Over time, chronic inflammation weakens the skin barrier and contributes to everything from premature aging to increased sensitivity and chronic skin conditions.

Visible Signs of Inflammaging (Inflammation + Aging):

• Dull, uneven complexion

• Fine lines and wrinkles

• Redness, rosacea, and flare-ups

• Loss of elasticity and skin sagging

• Slower wound healing

• Hyperpigmentation and blotchiness

How to Fight Inflammaging (Inflammation + Aging):

1. Antioxidants & Glutathione

Glutathione is your body’s master antioxidant and plays a crucial role in neutralizing free radicals. It also regenerates other antioxidants like vitamin C and E, making it a powerful force in your skin health arsenal. Supplementing with glutathione supports detoxification and calms inflammation, especially when combined with NAD+ and vitamin C for cellular repair.

2. Laser Rejuvenation & Fotona

Advanced laser rejuvenation treatments like Fotona 4D stimulate collagen, reduce inflammation, and tighten skin. This non-invasive technology uses multiple laser wavelengths to target different layers of the skin, reducing fine lines and improving elasticity from the inside out.

3. Lifestyle Modulation

Simple steps like prioritizing sleep, managing stress, daily movement, and eating anti-inflammatory foods (rich in curcumin) can significantly reduce your inflammaging load. Limiting alcohol, sugar, and processed foods while increasing hydration also enhances skin resilience.

4. Hormone Balancing

Fluctuations during perimenopause and menopause exacerbate inflammation, often leading to noticeable skin changes like thinning, dryness, and increased sensitivity. Bioidentical hormone therapy and functional wellness assessments can help restore balance and reduce inflammatory triggers.

5. Combination Beauty Treatments

Pairing Botox, Dysport, and regenerative skincare with internal wellness plans—including antioxidant supplementation and hormone support—creates synergistic, anti-aging outcomes. Treatments like microneedling, PRF, and radiofrequency can be layered with injectables for comprehensive skin revitalization.

Inflammaging (Inflammation + Aging) may be invisible, but its effects are not. By addressing the root cause through personalized, regenerative strategies, we help our patients age gracefully from the inside out.

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MEET THE DOCTOR

Dr. Vanden Bosch

Dr. Neda Vanden Bosch ("Dr. V") is an accomplished physician with over 17 years of practice and training in dermal fillers, collagen stimulators, laser and radiofrequency treatments, and skincare.  Dr. V holds medical licenses in 7 states and is board-certified by The American Board of Radiology and the American Board of Anti-Aging and Regenerative Medicine.  She is recognized nationwide as a top 1% injector of Sculptra Aesthetic and Restylane fillers.

"Advocating the proverbial 'ounce of prevention' approach, I favor doing 'a little bit all along' rather than waiting for substantial changes that make correction more costly."